Sentence examples for mutations can further from inspiring English sources

This suggests that PIK3CA mutations can further augment PI3K pathway activation mediated by other oncogenes such as ERBB2 (HER2) [ 10- 14].

Mutation can further improve amylase production by microorganisms, where UV and chemical treatment [ 29, 30].

Further the predicted R326H and R356Q mutations can be further studied by wet lab scientist to investigate the evidence of Tyrp1 protein mutation in association to OCA3 and develop a potent drug target for OCA3.

The striking influence of indel variants on the molecular evolution of flanking sequences strengthens the emerging general view that mutations can induce further mutations.

However, new findings of RAS (KRAS/NRAS) mutations that can further predict the therapeutic effects of anti-epidermal growth factor receptor (EGFR) antibody therapy necessitated a revision of the guidelines.

The oxidation induced by ROS can result in cell membrane disintegration, membrane protein damage and DNA mutation, which can further initiate or propagate the development of many diseases, such as cancer, diabetes, liver injury, arteriosclerosis and cardiovascular disease [ 3].

Additional studies may show that incorporation of similar mutations into EGF4KDEL 7Mut can further enhance its already potent anti-tumour activity.

However, the proposed method is not limited to (somatic) mutations alone and can further be extended to combine various types of genome data.

The causality of the mutation can be further examined by correcting the putative mutation with gene-editing approaches [e.g. transcription activator-like effector nuclease (TALEN) or clustered regularly interspaced short palindromic repeats (CRISPRs) Cas9 systems] and thereby generate genotype-matched iPSC control cell lines.

The mismatch repair (MMR) system repairs base base mismatches that result in point mutations and insertion/deletion loops that can further result in frameshift mutations [ 32].

Because the genome of a single mutant strain isolated after chemical mutagenesis can contain hundreds of mis-sense mutations (Sarin et al. 2010), SNP mapping is needed to narrow the interval in which candidate mutations can be found and then further analyzed to identify the causal mutations.