Sentence examples for mutations can extend from inspiring English sources

Many gene mutations can extend life--at least in fruit flies.

However, point mutations can extend their target spectrum to ceftazidime.

The remarkable variability in phenotypic severity observed in these newly "solved" Mendelian disorders raises interesting possibilities about the degree to which the phenotypic spectrum of single-gene mutations can extend.

Small numbers of variants were non-recoverable for d between 4 and 7. Based on these results, we can see that the blind spots for point mutations can extend as far as 7 bases from the edges of a read.> Multiple factors affect the extent of the variant calling blind spots.

When DNA-repair mechanisms fail, these mutations can lead to diseases such as cancer.

In model organisms it has been possible to demonstrate effects of mutations in genes that can extend lifespan nearly tenfold (Ayyadevara et al. 2008).

Genetic mutations reducing insulin-like signaling can extend adult lifespan in Caenorhabditis elegans, Drosophila melanogaster and, possibly, mice (Tatar et al., 2003; Baba et al., 2005).

Here, we present results indicating that the expulsion phenotype associated with ph mutations can be extended to a second model epithelium in Drosophila, the follicular epithelium of the ovary.

The set of somatic mutations can be extended to contain loss of heterozygosity (LOH) sites for which the non-reference allele is overrepresented in the cancer cell relative to a normal cell.

Although, the results were not statistically significant, probably due to the small number of cells evaluated, this suggests that mutually exclusive BRG1 and MYC mutations can be extended to other tumour types and that BRG1 may play an important role in neuroblastomas that are negative for MYC amplification.

Earlier studies have shown that Trp53 and Cdkn1a deficiencies can extend the development of several severe Brca1 mutations [ 13- 15].