Sentence examples for mutations can enhance from inspiring English sources
Increased germ-line mutations can enhance the opportunity for sexual selection, while sexual selection can reduce the mutation load.
In addition, mitochondrial dysfunction leading to mtDNA mutations can enhance cancer metastasis through increased ROS and apoptotic resistance [ 48, 49].
We have shown that incorporating models of molecular evolution to generate statements about tolerability of missense mutations can enhance the power of predictive medicine.
Both mouse models and human cases thus suggest that disease-associated APP and presenilin mutations can enhance the pathological accumulation of wild-type α-syn.
These results suggest that certain mutations can enhance HCCS activity, perhaps through altered heme/product-binding properties (e.g., increasing step 4, Release, see below and Discussion).
The fact that mutations can enhance cleavage suggests the possibility that the rate of LexA autoproteolysis may be finely tuned to be fast enough to facilitate robust SOS responses but slow enough to prevent aberrant SOS pathway activation.
Since the cpl1 mutation can enhance expression of other inducible promoters in addition to osmotic stress pathway genes [25], the three-component system with cpl1 is expected to be applicable for other inducible promoter-transcription factor combinations.
The atx2 mutation can enhance atx1 in reduction of expression of the flowering repressor gene FLC through reduced levels of H3K4me3 at the FLC locus [ 42].
This mutation can enhance FGFR3 activation in the absence of the ligand, which results in an increase in the dimerization propensity of the TM sequence alone in lipid bilayers and of the full-length receptor in the cell membrane.
APP673 mutation (A→V) and APP693 mutation (E→G) can enhance A β production and accelerate formation of amyloid fibrils.
Here, we advance this approach, showing that consideration of differences in mutation pressure can enhance the discrimination of disease/nondisease genetic variants.
