Sentence examples for mutations can change from inspiring English sources

Mutations can change the amino acids that a gene codes for, and hence the nature of the coded protein, or they can change the way that transcription factors do (or don't) bind to a given regulatory region.

In addition to resistance issues, HA mutations can change the tropism of viral binding (upper vs. lower respiratory tract binding) and the antigenicity of the virus.

Point mutations can change gene length in a few ways.

Even a few mutations can change the input from AND to OR or single input switches, suggesting that regulation is quite plastic and evolvable.

This assumption is justified if the phenotypes are determined by few viral protein functional determinants which are both independent and differ only few DNA bases, i.e. few mutations can change one determinant into another.

Crystal structure and biochemical analyses have also helped elucidate how different oncogenic PIK3CA mutations can change the PI3K architecture and promote oncogenicity dependent on the location of the mutated domain [ 31, 32].

Since 16S rRNA makes very specific contacts with many different ribosomal proteins and with other parts of itself, the pace at which spontaneous random mutation can change the sequence of the bases in the rRNA is slow.

It is worth mentioning that, in principle, one point mutation can change the oligomerization state of the coiled coil.

In some cases, the clinical penetrance of a particular mutation can change quite dramatically with age.

Importantly, a given mutation can change from a passenger to a driver aberration should the selective pressures change.

For instance, mononucleotide polymorphic mutation can change aa position 55 from Ala to Thr, which subsequently affects long-chain fatty acid hydrophobicity, fatty acid oxidation, and insulin resistance.