Sentence examples for mutations both in from inspiring English sources

Direct sequencing analysis was negative for small mutations both in CACNA1A and in ATP1A2 exons.

Thus, the double hit theory, mutations both in mitochondrial DNA and modifying genes aggravating the symptom, throws new light on mitochondrial dysfunction processes.

Mitochondrial damage can be inherited via mutations both in maternal DNA (mtDNA) and nuclear DNA, and present at birth or remain latent until triggered later in life.

It proves that JE virus is making possible modifications in antigenic structure through mutations both in nucleotide and protein sequences.

When we look at the genome sequence, both RP73 and RP45 carries stop mutations both in pchD, while PvdD protein is interrupted in RP73 only.

Our findings that KRASM cancers could respond to combinations of MEK + AKT inhibitors is interesting and other groups have shown MEK + AKT inhibitors could be effective in cells with mutations both in KRAS and PIK3CA [ 24].

There are only few reports about multidrug-resistance with mutations in both genes in patients after allogeneic haematopoietic cell transplantation (HCT).

The DYSF mutations in both alleles were found in 30 patients and only in one allele in four.

Mutations in PLEKHM1 in both human and the spontaneous incisors absent rat cause severe osteopetrosis.

Mutations in both genes were already present in the heterozygous state in the patient's germline.

Cloned p53 was sequenced and we found mutations in both alleles of p53 in DT40 cells.