Sentence examples for mutations at particular from inspiring English sources

It's known that melanoma risk is linked with mutations at particular genetic hot-spots.

By dispersing these sites across the genome, eukaryotes may limit the potentially deleterious accumulation of mutations at particular loci.

Subgroup analyses will be performed based on presence or absence of mutations at particular loci (eg, FBN-1 mutations) and, where possible, based on the predicted functional consequence of particular categories of mutation (eg, nonsense vs missense FBN-1 mutations) among those subjects with identified mutations.

The fact that all possible mutations at this particular site result in increased activity suggests that this region may function to constrain the G protein coupling of the receptor, a constraint which is normally relieved by agonist occupancy.

Such biases could potentially arise from the positioning within the phylogenetic tree of the mutations at a particular site.

Mutations at this particular site are typically connected with resistance to NNRTI drugs only.

Large lag loads are needed because these loads indicate maladaptation, and that, in turn, increases the target size for adoption of advantageous mutations at a particular locus.

A test of multinomial homogeneity in our context is a test that, given the count of synonymous and nonsynonymous mutations at a particular site in both the selected and unselected populations, asks if the the counts are compatible with the hypothesis that the mutation frequencies are equal.

There is substantial evidence for the evolution of elevated mutation rates at particular loci or traits in response to fluctuating environments (Jansen and Stumpf 2005).

Theoretical models predict the evolution of elevated mutation rates at particular loci under temporally fluctuating selection (Ishii et al. 1989; Travis and Travis 2002), particularly at intermediate levels of fluctuations (Travis and Travis 2002).

Our results contrast with those of a very recent American study proposing that patients with fibromatosis harbouring an S45F mutation are at particular risk of recurrence (Lazar et al, 2008).