Sentence examples for mutations at numerous from inspiring English sources

Causing collateral damage to the B-cell genome during CSR and SHM, AID induces unwanted (and sometimes oncogenic) mutations at numerous non-immunoglobulin gene sequences.

In a previous study [32], mutations at numerous positions of subunit N of the E. coli Complex I resulted in the loss of enzyme activity, but several mutations at E154, K158, H224 and Y300 also caused reduced ability to utilize exogenous decylubiquinone in NADH oxidase activity.

Risks were summarized [see Additional file 1] for leukemias and lymphomas vs. mutations or aberrations at numerous steps within the model pathway in Figure 1.

This program models the evolution of genomic sequences in a population under the influx of numerous mutations at multiple loci and can take into account dozens of parameters/variables simultaneously.

Heterogeneity of biomarkers is becoming increasingly recognised to occur at numerous levels, including different mutations across a single tumour as well as between lesions in a single patient.

However, such tight linkage can potentially limit the effectiveness of purging via selfing if deleterious mutations at multiple loci are too numerous to segregate out among a fixed number of offspring [22].

Numerous independent back mutations at nucleotide positions (nps) 64, 146, 152, 153, 16111, and 16362 are evident (that on their own do not justify support for subhaplogroup naming).

This clinical diversity is reflected in genetic heterogeneity, and at present more than 30 genetic loci have been mapped, with causative mutations in numerous genes identified [ 2– 4].

Because each cell harbors numerous mitochondria with multiple copies of mtDNA, mutations at mtDNA can be heteroplasmic (variably mutated mtDNA copies co-exist in the same cells) or homoplasmic (all mtDNA copies carry the same mutations).

Prase has been found at numerous localities.

Our bodies accumulate lipofuscin and oxygen free-radical damage and random DNA mutations and numerous other microcellular problems.