Sentence examples for mutations at a from inspiring English sources

Genes that accumulate somatic mutations at a higher than stochastic rate are referred to as 'significantly mutated genes' (SMGs) and are considered likely drivers of malignant progression.

By making mice with only one or a few suspect mutations at a time, scientists cut through the chaotic genetic noise.

For example, the genotype phenotype map can be described in terms of the number of traits the mutations at a gene affect (pleiotropy), how many genes affect the same trait (polygeny), distribution of effect sizes, etc.

Most techniques aimed at detecting mutational events within a gene, such as digital droplet PCR or SNV array technologies, detect specific base-pair substitutions or frameshift mutations at a defined genomic locus rather than across the entire gene length.

Many new mouse mutations are being developed through large-scale mutagenesis screens that use chemicals such as N-ethyl-N-nitrosourea to induce point mutations at a high rate.

P-endosymbionts also accrue slightly deleterious mutations at a faster rate than free-living bacteria [6].

Such biases could potentially arise from the positioning within the phylogenetic tree of the mutations at a particular site.

Also, the M mitochondrial genome accumulates mutations at a high rate [25] which may obliterate a primer recognition site.

Having fewer negative pleiotropic consequences of mutations at a locus translates to less evolutionary constraint (or higher net selection coefficients).

Dissecting the dynamics of these escape mutations at a population-level would help to understand how HLA-mediated selection drives the evolution of HIV-1.

These studies provided evidence that the predicted proteins of extensively edited genes accumulate mutations at a higher frequency than their unedited homologues in closely related species.