Sentence examples for mutations around from inspiring English sources

According to BIC database [ 10] the majority of the pathogenic mutations in BRCA1/2 are frameshift mutations (around 70%%), while nonsense and missense mutations contribute with around 10%% each.

55 56 Although the risk of CRC development in ulcerative colitis is increased, the high frequency of these mutations (around 40% of patients) should actually result in far more cancers.

Considering our data, it seems that among those subjects that are expected not to have codon 12 or 13 mutations (around 60% of mCRC patients), testing for BRAF and rare KRAS mutations would exclude around 25% of patients, with obvious saving of economic resources and sparing unnecessary toxicities.

TP53 in endometrial carcinoma has a landscape of mutations that can be considered borderline for both the OG-S and TSG-S definitions, with a consistent number of diffuse truncating mutations (around 20%) and a concentration of missense mutations on the DNA binding site.

BRAF mutation and MSI status were not determined in this study cohort, as the prevalence of BRAF mutations (around 2% (Gaedcke et al, 2010; Derbel et al, 2013)) and MSI (around 2% (Slattery et al, 2009)) is very low in rectal cancer.

But most mutations are neutral in their effect.Sexual reproduction mixes up the DNA, distributing neutral mutations around the population.

Some genes and traits, such as an organism's method of reproduction, can even put their proverbial thumb on the scale and affect which mutations stick around in a population.

So why has this cancer-causing mutation stuck around?

Scientists believe that was due to a mutation around 2013, roughly the time the medical community began to blame the virus for horrific birth defects.

Since 7 8% of Icelandic breast cancer patients carry the BRCA2 founder mutation, around 125 positive cases were expected from this subgroup.

Our contribution is to highlight that the CFTR peptide sequence straddling the site of the commonest (by far) mutation around F508 bears striking similarities with a range of pathogen proteins.