Sentence examples for mutations are well from inspiring English sources

The variability of the natural history and prognosis as a function of different ATP1A2 mutations are well known.

In the case of cancer, mutations are well documented to arise in key oncogenes and critically important tumor-suppressor genes as part of the disease progression process.

Our findings demonstrate that B-RAF and N-RAS mutations are well preserved during short term in vitro propagation and, most importantly, differentially impact the outcome of melanoma patients.

While the effects of genetic drift on the fixation of deleterious mutations are well appreciated and studied, for example in Phase 1 of Wright's Shifting Balance Theory [24], the effects of stochasticity on the fixation of beneficial mutations have not been considered in any experimental context.

Objectives: DNA damage and mutations are well established for their carcinogenic effects.

IDH1 and IDH2 mutations are well known in gliomas [ 6], but are notoriously difficult to grow in culture [ 7].

It was suggested (Reetz 2013; Skinner and Terwilliger 1996) that additive effects might occur when the locations of mutations are well-separated.

The effects of the mutations are well-correlated among the three subunits.

Most of these mutations are well-known hotspots in the phylogeny [44], with the only exception of m.4674A>G that appears as a private substitution in two patients and which received two hits in Soares et al. [44] (Table 2).

Variability of phenotypes associated with mtDNA mutations is well recognized [ 13].

Worldwide variation in the distribution of BRCA1 and BRCA2 mutations is well recognised (Szabo and King, 1997).