Sentence examples for mutations are virtually from inspiring English sources

Although the evolution of self-compatibility may confer short-term advantages, it is predicted to increase the risk of extinction in the long term because loss-of-function mutations are virtually irreversible.

Consequently, the profiles of the temperature dependence of the phase relaxation rate of FeS cluster in all samples having the heme reduced (regardless of the absence or presence of inhibitors or mutations) are virtually the same.

In fact, contrary to the number of potential factors causing time-dependent rates [ 31], synonymous mutations are virtually neutral and not subject to the effect of purifying selection, even though saturation might still be an issue with long time frames.

Because previous genotyping data have demonstrated that homoplastic SNP mutations are virtually nonexistent in F. tularensis (20, 25 ), a common mutation at Ft-SNP1 indicates that the isolates in genetic subgroup 1d in Örebro and 1e in Ljusdal share a more recent common ancestor than they do with isolates of subgroups 1a, 1b, or 1c in Örebro.

Substantial tumor multiplicity was found, but K-ras and p53 gene mutations were virtually absent.

This indicates that the more common c.2904-2905delAG mutatisn is virtually exclusively encountered on the AHAP17 haplotype, but that mutation-free versions of the latter also exist.

The BRAF K601E mutation is virtually restricted to the follicular or solid variant and is present at up to 9% [ 6, 18].

When mutant cells divide, they give rise to more mutant cells since the probability of correcting a mutation is virtually zero [ 5, 6].

This distinguishes them from BRAF mutations which are virtually absent in precursor lesions of PTCs.

Deleterious alterations, as deduced by mutation type, are virtually absent in BC-only families, and very few BC cases with a BC/OC family history have been experimentally proven to carry a truncating RAD51C mutation [ 1- 4].

Recent data of The Cancer Genome Atlas (TCGA) consortium on lower grade (WHO grade II and III) gliomas show that IDH mutations in these gliomas are virtually mutually exclusive with homozygous deletion of CDKN2A and with amplification of EGFR [ 1, 12].