Sentence examples for mutations are viable from inspiring English sources

Mice heterozygous for Rlf mutations are viable, with no overt abnormalities.

General knockdown of the gene caused great reduction in larval viability, whereas existing nopo mutations are viable and sterile (Merkle et al. 2009).

DOI: http://dx.doi.org/10.7554/eLife.03383.005 Although clones of mutant cells display a clear growth advantage, flies homozygous for each of these Fbxl7 mutations are viable and fertile.

Finally, the cancer process, when considered from the cell point of view, is extremely inefficient at many stages: in the initiation as well as during the progression, when only rare mutations are viable and improve cell competiveness.

The fact that the dRASSF mutations are viable might therefore reflect the facts that its ability to regulate the Hpo pathway may be redundant with other modes of regulation and that loss of dRASSF's tumor-suppressive activity is balanced by loss of its growth-promoting activity.

Supporting this notion, murine transgenic models harbouring different, heterozygous, TRα mutations are viable and exhibit recognisable abnormalities, but with little perturbation of thyroid function [9 12]; such absence of an overt biochemical, thyroid, phenotype likely explains why the homologous human disorder had eluded discovery.

Heterozygotes for the eIF3h MommeD12 and eIF3h mutationsmutations were viable and fertile.

Animals carrying this mutation are viable but present with growth retardation, polysyndactyly and tooth developmental abnormalities [13], [18].

Drosophila homozygous for this mutation are viable and fertile as previously observed for the Wwox mutants.

Mice that are homozygous for the targeted mutation are viable and fertile and do not display any gross behavioral abnormalities.

Mice that are heterozygous for the targeted mutation are viable and do not display any gross behavioral abnormalities.