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Background: In chemical genetics, small molecules instead of genetic mutations are used to modulate the functions of proteins rapidly and conditionally, thereby allowing many biological processes to be explored.
Therefore, in addition to chromosomal alterations, FGFR3 mutations are used as a clonal marker.
KRAS mutations are used as negative predictors of antiEGFR therapies in colorectal cancer [ 38].
The process is repeated 90 times to ensure that all subsets of mutations are used for each purpose.
These mutations are used to run a genotypic interpretation algorithm that provides an estimate of the expected levels of resistance to all currently used antiretroviral drugs.
There are 258 mutations in our data set, each time one mutation is taken as the test data and the remaining 257 mutations are used to train the model.
Similar(52)
Wild-type GFP-muskelin and a panel of alanine point mutations were used to test the sensitivity of self-association to PKC activation.
Mutations were used to determine the position of PTCs as outlined above.
The independent test set of RET curated mutations was used to evaluate performance of different categories of classifier algorithms.
The following mutations were used.
Both synonymous and nonsynonymous mutations were used.
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transfer are used
mutations are summarized
mutations are associated
mutations are known
mutations are seen
mutations are observed
mutations are spread
mutations are detected
mutations are mapped
mutations are kept
mutations are located
mutations are replicated
mutations are implicated
mutations are termed
mutations are able
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