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Additionally, using knowledge obtained from the simulations, specific mutations are suggested and the desired structure and pose on the surface is obtained.
A few mutations are suggested that might have an effect on differential binding/regulation.
Interestingly, these mutations are suggested to modify the severity of the HCM phenotype but not cause it per se.
Although a low expose of smoking reduces the risk for lung cancer, EGFR mutations are suggested to be related to the occurrence of lung adenocarcinoma in nonsmoker.
MAD1L1 is a component of the mitotic spindle-assembly checkpoint, and its mutations are suggested to play a role in the pathogenesis of various types of human cancer (e.g., [ 52]).
Although coexistent mutations of AKT1 and PIK3CA mutations are suggested to be infrequent in breast cancer (Carpten et al, 2007; Bleeker et al, 2008), it remains to be elucidated whether AKT1 mutations are mutually exclusive with all the other PI3K AKT-activating alterations in various tumour tyPI3K AKT-activating
Similar(54)
The effects of some of these mutations were suggested to root in a stabilization of intra-molecular base pairing in U6 snRNA.
In previous small studies of this cancer, ras mutations were suggested to be related to wood dust exposure, but these studies were too limited to detect statistically significant associations.
These results suggested that, the effect of these mutations into the parent genome was smaller than the increase of growth rate in the cultivation from 216 to 576 h, even though in some clones no mutations was suggested to be fixed on the genome.
We sought mutations in the EGFR gene in TNBCs, because EGFR mutations were found in a subset of Japanese non-small lung cancers, despite being very rare in Caucasians [ 23], and because these mutations were suggested to predict responses to gefitinib therapy [ 23, 24].
A glimpse of the complexity that lies in exploring H3K27 mutations is suggested by their inherent nature to alter global levels of H3K27me3, even though in the case of H3.3K27M mutations H3.3 is a minimal contributor to total histone H3 levels [ 43].
More suggestions(15)
transfer are suggested
mutations are summarized
mutations are observed
mutations have suggested
mutations are sequenced
mutations are underlined
mutations are mapped
mutations are kept
mutations are replicated
mutations are termed
mutations are known
mutations are highlighted
mutations are introduced
mutations are summarised
mutations are identified
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com