Sentence examples for mutations are robust from inspiring English sources

Although we have previously demonstrated that NGS methods for the detection of FH mutations are robust and more sensitive than standard methods, including Sanger sequencing [24], we recognise that Sanger re-sequencing of the FH genes in our cohort could provide additional evidence that no mutations were missed.

Furthermore, they are extended to allow for recurrent mutations, which are robust to high mutation rates and mutation hot-spots.

As we studied a large number of unselected cases with good representation of index mutations, the results are robust and directly relevant to current management of mCRC.

Nonetheless, with consistent observations noted in all of these analyses, the weight of evidence from the studies reviewed here suggests that RAS mutations are a robust biomarker for a lack of EGFR-targeted mAb activity.

On one hand, signaling circuits are robust to mutations and environmental fluctuations [ 56].

Structurally, it is known that scale-free protein-protein interaction networks are robust toward mutations unless those attacks are targeted at a hub node [ 4, 10].

Recent computational studies have been mainly focused on precursors of miRNAs [ 10- 13] and on viruses [ 14- 16], and have suggested that natural RNA sequences are robust to mutations.

On evolutionary time scales, robustness to genetic change has an important consequence on the genetic constitution of a population: It allows mutations to accumulate that are not phenotypically visible, precisely because phenotypes are robust to such mutations.

These statistical approaches are robust to the nonneutral effects of mutations on folding stability at the whole gene level.

Financial exchanges are robust.

Its capital ratios are robust.