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Exact(9)
"If children of older fathers don't reproduce, harmful mutations are removed from the gene pool".
Purging can prevent fitness loss only if all newly arising deleterious mutations are removed from a lineage.
Mutations are removed if their frequencies are lower than a certain threshold (default 0.1).
On average, about 90% of amino acid-changing mutations are removed by strong purifying selection.
Negative selection (purifying selection) is the process by which deleterious mutations are removed.
Sex separates individual mutations, which allows selection to operate on them independently: beneficial mutations are maintained, and detrimental mutations are removed, more effectively.
Similar(51)
For this study, all subjects analyzed were white and families with known parkin mutations were removed.
Therefore, theses mutations were removed by meiotic recombination.
During this step, silent mutations were removed.
nsSNPs that overlapped with identified disease mutations were removed.
Putative pseudogenes, e.g. ones with frameshift mutations, were removed from the analysis.
More suggestions(15)
adjustments are removed
mutations are summarized
mutations are known
mutations are seen
mutations are observed
mutations are based
mutations are mapped
mutations are detected
mutations are kept
mutations are replicated
mutations are selected
mutations are located
mutations are implicated
mutations are found
mutations are termed
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CEO of Professional Science Editing for Scientists @ prosciediting.com