Sentence examples for mutations are quickly from inspiring English sources

DNA sequence comparisons with multiple primate species have revealed near-conservation of alleles at variant loci in humans providing conclusive evidence that new mutations are quickly eliminated.

While some new mutants have higher fitness than others and therefore are retained by positive selection, most mutations are quickly removed by purifying selection because they are deleterious [ 5, 6].

Polymorphism-based approaches require the action of relatively recent positive selection, as patterns of variation indicative of selection (such as patterns in the site frequency spectrum [SFS] or linkage disequilibrium [LD] between mutations) are quickly obscured by subsequent mutation and recombination events, as well as genetic drift (Kim and Stephan 2002; Przeworski 2002).

Views on the mode of evolution of genes of the innate immune system are opposing: 1) natural selection has functionally optimized these genes so that newly arising mutations are quickly lost from a population; or 2) these genes co-evolve with rapidly evolving microbes (Parham 2003; drawing support from Haldane 1949).

The phenotype of germline SDHD mutations was quickly extended to include thoracoabdominal PGLs (TAPGLs) and PCs (Gimm et al. 2000, Astuti et al. 2001 a ).

Newly arising mutations, therefore, are quickly removed from the population, providing genomic signatures that are consistent with purifying selection.

Such mutations are more likely to result in non-functional proteins, and in turn, the mutant alleles are quickly removed from the population.

Our study provides evidence that genes of the cell-surface TLRs, that is, TLR2 and TLR4, have been so optimized to defend the host against microbial infections that new mutations in these genes are quickly eliminated.

We point out that while mutations to tolerate aneuploidy are quickly selected in lab studies (driven by the strong selective pressure to overtake sickly aneuploids), here we are selecting for the loss of aneuploidy, which provides a mild fitness benefit.

After determining the rough position of a mutation on a chromosome using chromosome mapping, mutations can be quickly mapped to a genetic interval using the same efficiencies of the 96-well format employed in chromosome mapping.

Moreover, mutations causing resistance to such insecticides would probably seriously affect fertility and individuals carrying the mutations would be quickly eliminated from the population.