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Kras is mutated in CT26 [ 5] but other mutations are not known.
Mutations are not supposed to revert spontaneously".
Therefore, the recF143 and recB21 mutations are not leaky.
Part of the difficulty is that the options for women with BRCA mutations are not appealing.
So nearly neutral mutations are not totally noise, and may be related to some quantitative characters.
Many of the mutations are not in genes themselves, which are used by cells to make proteins.
However, this assumption is invalid when mutations are not rare in a whole population.
Thirty eight of the identified tuning mutations are not found in known microbial rhodopsins.
These mutations are not distributed at random, and bladder-specific mutation hotspots have been reported at codons 280 and 285.
These mutations are not common -- they cause less than 10percentt of all breast cancers -- but they greatly increase a woman's risk, to 36percentto85percentcent.
Base excision repair helps ensure that mutations are not incorporated into DNA as it is copied.
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