Sentence examples for mutations are mutually from inspiring English sources

Similar to glioma, IDH1 and IDH2 mutations are mutually exclusive, though the mutational frequency of IDH in AML is much lower (23%) (Chou et al., 2011b; Ward et al., 2010).

ret activation is not exclusive of ras or BRAF mutation, whereas ras and BRAF mutations are mutually exclusive.

Most interestingly, PBRM1 and BAP1 mutations are mutually exclusive in ccRCC, and in a side-by-side comparison, PBRM1 mutation correlates with improved OS over BAP1 alterations (Kapur et al., 2013; Pena-Llopis et al., 2013).

Further, they showed that TET2 and IDH mutations are mutually exclusive in AML, result in overlapping methylation signatures, and impair HSC differentiation in 32D myeloid cells (Figueroa et al., 2010).

Interestingly, BRAF mutations are mutually exclusive with NRAS mutations in melanoma and KRAS mutations in colorectal cancer [7], [12], [13].

Irrespective if these mutations are mutually exclusive or not, the evidence for a strong negative association between these two genes is compelling [4], [18], [21].

When combining results from the four studied factors, only two patients had both BRAF and KRAS mutated in the NSHDS cohort, while BRAF and KRAS mutations were mutually exclusive in the CRUMS cohort.

BRAF mutations and KRAS mutations were mutually exclusive [5].

KRAS and BRAF mutations were mutually exclusive, whereas, three tumours carried both KRAS and PIK3CA mutations.

KRAS and BRAF mutations were mutually exclusive in the total series.

Thus, in the Taiwanese samples analyzed, p53/KRAS mutations and c-CBL mutations were mutually exclusive (data not shown).