Sentence examples for mutations are lost from inspiring English sources

Of course, many beneficial mutations are lost by random drift while they are rare.

Most early mutations are lost because most stem cell lineages become extinct during crypt clonal evolution.

Stochastic selection creates drift, where low frequency mutations are lost despite intrinsically high adaptation scores.

This is because all mutations start at a low frequency, and most mutations are lost before reaching substantial allele frequencies.

Somatic evolution is suppressed because only mutations that occur in stem cells are retained, while most other mutations are lost.

During this process numerous genetic mutations are lost from the population while mutations which occur concurrently with drug resistance causing mutations (or 'hitchhiking SNPs') remain [ 14].

Most baseline resistance mutations were lost in subject 7 during treatment interruption becoming undetectable even by deep sequencing at the time of virological failure.

Alternatively, perhaps background enhancer mutations were lost, though outcrossed strains were used for the constructions.

Second, the fact that relatively large-effect beneficial mutations were lost in competition supports the finding that beneficial mutations may be much more frequent than believed [ 40, 41].

However, it has been claimed that the prognostic significance of IDH1 mutations is lost in glioblastoma patients older than 50 years (Boots-Sprenger et al 2013), who comprise 71% of our glioblastoma patient population, this probably accounting for our inability to substantiate the prognostic utility of IDH1-R132H in our series.

The likely large costs associated with changes to the EGFR are further exemplified in this study, because after some patients with resistant cancers stopped treatment with TKIs, the resistance mutations were lost, and their tumours once again became sensitive to treatment by either the same or a different EGFR inhibitor.