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Exact(37)
That means crucial mutations are more likely to happen, but also that in any given cancer there is a lot of mutational "noise".Until now, this has made it more difficult to discover which mutations are important and which merely incidental.
The arduous job is to figure out which mutations are important, a task that requires skill, experience and instincts.
One would be distinguishing which mutations are important, because many of those found would have nothing to do with cancer.
Methods for introducing multiple site-directed mutations are important experimental tools in molecular biology.
Normal DNA sequencing cannot distinguish which mutations are important and which are not.
Comparing cancerous tissue from different individuals will show which mutations are important.
Similar(23)
As ENF will be introduced to Hong Kong, an understanding of the prevalence of naturally occurred ENF resistance mutations is important before implementation of ENF treatment.
The development of simple, reliable, and rapid approaches for molecular detection of common mutations is important for prevention and early diagnosis of genetic diseases, including Thalessemia.
A deep understanding of the resistance mechanism conferred by these mutations is important to the design and discovery of more new effective drugs against resistant HCV strains.
Elucidating how the metal site of SOD1 can be disrupted by ALS-linked mutations is important for a better understanding of the pathogenesis of the disease and for developing more efficient treatments.
Subsequent genetic analyses carried out by other scientists on viruses, bacteria, yeast, fruit flies, and nematodes demonstrated that the intentional induction of mutations that disrupted the genetic code, combined with the analysis of observable traits (phenotypes) produced by such mutations, were important approaches to the study of gene function.
More suggestions(15)
mutations are crucial
mutations are prominent
move are important
deployment are important
transfer are important
mutations are deleterious
mutations have important
mutations are irrelevant
mutations are accidental
mutations become important
mutations play important
mutations are responsible
mutations are necessary
mutations lack important
mutations are rare
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com