Sentence examples for mutations are highly from inspiring English sources

She and other women with BRCA1 or 2 mutations are highly likely to develop breast cancer at some point in their lives.

It also adds that somatic de novo mutations are highly variable, may depend on tissue and age of the individual, and could add to predisposition for disease.

Regardless of the mechanism of change, these mutations are highly specific.

Hence, these results suggest that point mutations are highly dependent on replication errors, while genome rearrangements are not.

The results indicate that while point mutations are highly replication-dependent, genome rearrangements are as easily induced in non-dividing cells as in mitotically active ones.

The extreme evolutionary pressure to maintain these residues implies that resistance mutations are highly unlikely to develop, which makes them attractive chemotherapeutic targets.

PIK3CA kinase mutations were highly clonal, more frequent in AR + vs.

Mutational frequency and type of somatic point mutations were highly variable among the different MPNSTs modeled, but very consistent when comparing primary tumors with matched orthoxenografts generated.

The explanation of this phenomenon is that dark moths, which originally were chance mutations, were highly visible to predators when resting on lichen-covered trees during the day.

In particular, the distribution of mutations is highly associated with intrinsic molecular processes including transcription, chromatin organization, DNA replication timing, and DNA repair.

Genetic diagnosis in HHT is difficult, as mutations occur in numerous different locations in the linked genes, without particular mutations being highly frequent (as opposed to, for instance, the ΔF508 mutation in cystic fibrosis).