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Exact(35)
BRAF mutations are frequent in melanoma but their prognostic significance remains unclear.
(2015) demonstrate that passenger mutations are frequent in most genetically engineered congenic mice and persist even after extensive backcrossing.
In T-ALL, NOTCH mutations are frequent, occurring in about 55 60% of pediatric and adult T-ALL samples [2], [18].
Mitochondrial DNA mutations are frequent in various tumor types [3], and detected in preneoplastic lesions thereby indicating their occurrence at early stages of multistage tumor progression [5].
NPHS1 mutations are frequent in Finland.
p53 mutations are frequent in MNU-induced rat colon tumors.
Similar(25)
We tested the hypothesis that these mutations were frequent in cancer genes, by studying again TP53.
As expected, homozygous mutations were frequent in six tumor suppressor genes (81%), with the exception of APC, while the five oncogenes also had a relatively high frequency of homozygous mutations (20%).
TET2 mutations were frequent in RAEB1 (7/16, 43.8%).
RUNX1 mutations were frequent in our series of CMML.
RAS pathway-activating mutations were frequent (38/79; 48.1%), which is in line with recent studies.
More suggestions(15)
mutations are prevalent
mutations are often
mutations are recurrent
deployment are frequent
mutations are recurring
transfer are frequent
mutations are deleterious
mutations are irrelevant
mutations are accidental
mutations are responsible
mutations show frequent
mutations are necessary
mutations are beneficial
mutations are neutral
mutations are unknown
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