Your English writing platform
Discover LudwigSuggestions(2)
Exact(1)
Under these conditions, the fates of all mutations are determined stochastically by genetic drift and mutations are free to accumulate independently of their fitness effects (with the exception of lethals).
Similar(59)
Despite the low bootstrap support, all but the three above-mentioned mutations were free of homoplasy (which is reflected by very high retention and consistency indices in the parsimony analysis, see Figure 3) and can therefore be considered as diagnostic.
The patient whose uveal melanoma carried the TERT mutation is free of disease at 31 months after diagnosis but an effect of the mutation in the TERT promoter on the metastasis risk cannot be definitely excluded.
Humans with recessive loss-of-function Nav1.7 mutations are pain free (Cox et al., 2006, Goldberg et al., 2007), but specific high-affinity antagonists of Nav1.7 have so far not produced dramatic analgesic effects (Schmalhofer et al., 2008).
The simplest model is used to answer the first question by performing both simulations in which all R genomes carry deleterious mutations and simulations in which all R genomes are free from deleterious mutations.
With the advent of inexpensive DNA sequencing methods, highly informative specific-locus mutation rates and spectra can be constructed based upon hundreds of mutations collected under conditions that are free from selection perturbations.
Single base mistakes can also be repaired by site-directed mutagenesis, and/or by reconstructing the final gene from sub-cloned gene fragments that are free of mutations.
We further assume that initially all genomes are free of deleterious mutations and that back-mutations do not occur.
Although some mutations are symptom-free, they exert an effect on the body.
A study into mitochondrial diseases, which are maternally inherited, has shown for the first time that it is possible to produce healthy stem cells that are free of genetic mutations by engineering the skin cells of an affected patient.
Type z represents a haploid genome with wild-type second and third chromosomes that are free of lethal mutations at the start of experiment.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com