Sentence examples for mutations are first from inspiring English sources

A recent study with regard to tumor vaccination showed a proof-of-concept in which somatic mutations are first detected using NGS.

It is noteworthy that recent study showed a proof-of-concept in which somatic mutations are first detected using NGS, then the immunogenicity of these mutations is defined, and finally, mutations are tested for their capability to elicit T cell immunogenicity [ 15].

DNMT3A somatic mutations were first discovered by Yamashita and colleagues following sequencing of tissue from adult patients with de novo acute myeloid leukemia (AML) (Yamashita et al., 2010).

IDH mutations were first observed in human gliomas [ 102].

IDH1 and IDH2 mutations were first described in gliomas.

Such mutations were first described in the Notch1 gene in T cell acute lymphoblastic leukaemia.

FBXW7/hCDC4 mutations were first identified in breast cancer and ovarian cell lines [ 14, 35].

Homozygous PINK1 mutations were first described in three consanguineous families (Valente et al. 2004).

Sensitive mutation analysis was performed on all samples collected from this patient after mutations were first detected by Sanger-sequencing.

BRCA1 & 2 mutations were first identified in 1994 and are BC risk factors for some specific groups [ 75].

In 2004, these mutations were first identified in patients with non-small cell lung cancer (NSCLC)[ 1].