Sentence examples for mutations are extremely from inspiring English sources

31 Either (G151R) or (L168R) is present in 99% of KCNJ5-mutated APAs, whereas the five other mutations are extremely rare.

The gene mutations are extremely rare and together account for a tiny fraction of autism cases — in these studies, only a handful of children.

Exon 18 mutations are extremely rare comprising of 4.1% of all EGFR mutations and the delE709_T710insD mutation accounts for only 0.16% of mutations when occurring as a sole mutation, however, the frequency can vary with the kit utilized for testing.

These mutations are extremely heterogeneous, thus residual enzyme activity can be expected in certain cases which possibly explains the high variability of the disease severity [23] [26].

Since non-silent mutations are extremely rare in oprL, the conservation of distinct alleles within a clonal complex or clone is likely the result of a genetic linkage or co-selection.

This approach is not viable for the situation we have outlined above where double mutations are extremely likely and the design, synthesis, and analysis of further probes will be costly when applied to a wide range of patients.

In summary, KRAS mutations were extremely rare, and the BRAF mutation was absent in a nonbiased database of 203 ESCCs.

Crossing between mouse strains harboring various FGFRs mutations is extremely important to elucidate the interactions between different FGFRs.

In our sample, we found that p14 ARF mutations were extremely rare; we detected only a previously reported point mutation in one sample (1/98; 1%).

The frequency of p14ARF mutations was extremely low (1/98; 1%), whereas coexistence of methylated and unmethylated alleles in both tumors and normal colon mucosa was common (91/98; 93%).

This and many other examples (including those described in the paper) suggest that the problem of dominant mutations is extremely complex.