Your English writing platform
Discover LudwigExact(8)
However, if strongly deleterious mutations are common, then indirect selection against a mutator can act over the short term to inhibit mutator hitchhiking in situations where recessive deleterious mutations are expressed.
The importance of intermediate filaments in muscle is further strengthened by murine models in which genetically designed intermediate filament mutations are expressed, leading to progressive skeletal or cardioskeletal myopathy in affected mice.
Since their recessive mutations are expressed in an easily identifiable nonlethal phenotype, both glutinous and sweet maize have been easy targets of artificial selection.
These "polymerase stabilizing" mutations are expressed in HBsAg close to or in the "a" determinant and reduce HBsAg immunoreactivity (40 ).
We therefore expect selection to act more efficiently when mutations are expressed in males, the result of which could be reduced genetic load on the X.
At this point, they could also understand how variations arise through mutations and how these mutations are expressed as changed amino acids with altered properties.
Similar(52)
Interestingly, expression levels of Fra-2 containing S320A and/or T322A mutations were expressed at lower levels in addition to the loss of the slower mobility (High-Mr) band.
We find that the distribution characterizing selection coefficients of new mutations is expressed in terms of a number of geometrical invariants associated with mutation, selection and the parental phenotype.
These data suggest that the specific phenotype(s) associated with the E2 mutations introduced into strain Ag41855 would be retained if these mutations were expressed in other CHIKV strains.
Most of these mutations were expressed as frameshifts or splicing errors and resulted in no or very little IL2RG mRNA being expressed as shown in Figure 1d probably due to nonsense-mediated decay.
Some interesting observations were made when the combinatorial mutations were expressed in C2C12 cells.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com