Sentence examples for mutations are exposed from inspiring English sources
For example, recessive mutations are exposed to selection in the hemizygous X of males.
This implies that at least some mutations are exposed rather than masked by the activity of molecular chaperones.
Not all inbreeding leads to inbreeding depression; it does so only if deleterious recessive mutations are exposed to selection in the homozygous state (Fig. 4).
On the basis of our data, Figure 2 suggests that patients with tumours harbouring a 'sensitive' c-KIT genotype (KIT exon 11 mutations) are exposed to concentrations that are already near the top of the concentration response curve (as was probably the case in our CML patients; see above).
One difference between sexual and asexual treatments is that only the sexual lines produced haploid spores, and here recessive or semi-dominant mutations were exposed to selection.
None of the cases with tumours with K- ras mutations were exposed to other potential confounders, i.e. leather and textile dust, nickel and chromium VI).
Consequently, it is often seen in cells with a lax G2/M checkpoint control (e.g. p53 mutation) being exposed to genotoxic stress.
Two gefitinib-sensitive NSCLC cell lines HCC827 and PC9, both harboring EGFR exon 19 in-frame deletion mutation, were exposed to increasing concentrations of gefitinib and generated GR cells as reported previously.
This raises the question whether patients with intellectual disability caused by SWI/SNF mutations in the germline are exposed to an increased risk of developing cancer.
Hemizygous genes are particularly good candidates for evaluating evidence for coadaptation and/or sexual conflict because of their relatively older age (Hough et al. 2014), and because beneficial mutations in such genes are exposed to positive selection regardless of dominance and may therefore spread more rapidly.
Dominant or partly dominant mutations on X or Z chromosomes are exposed to selection twice as often in the homogametic as in the heterogametic sex.
