Sentence examples for mutations are essentially from inspiring English sources

BRAF mutations seem prevalent in MIN, whereas TP53 mutations are essentially found in CIN.

TE-generated mutations are essentially stochastic in nature, and many of them will have negative impact on survival.

Mutations are essentially random, occurring as independent events throughout the lifespan of an individual, potentially accelerated by exogenous carcinogens or DNA repair defects.

Notably, MDM2 amplification and p53 mutations are essentially mutually exclusive and, in the past few years, small-molecule antagonists of p53 MDM2 interaction as nutlins or MDM2 inhibitors have been developed.

Finding mutations is essentially a search for disorder.

β-Catenin missense mutations were essentially found at codons 41 and 45, identified as c.121 A>G or pThr-41-Ala (T41A), c.133T>C or pSer45Pro (S45P), and c.134C>T or pSer45Phe (S45F).

Individuals from Li Fraumeni families who have an inactive p53 gene due to a germ-line mutation are essentially born with 'initiated' cells, and 90% of these individuals develop cancer by age 70 years.

The smn-1 ok355 smn-1 ok355s essentially a null allele, albeit retaining progressively decreasing levels of mutation SMN-1.

Unlike DNA mutations, which are essentially irreversible in cancer, chromatin alterations, including both histone modifications and nucleosome remodeling, are potentially reversible and thus might constitute attractive therapeutic targets (Wilson and Roberts, 2011).

Comparing the two studies, the SNM mutation rate estimates are essentially identical (when we include SNMs from double and complex mutations), the SNM spectrum and the indel bias are essentially identical, and mutations in flocculin genes are overrepresented.

The double knock-out mutations irx7/irx7L and irx9/irx9L are essentially lethal [ 18].