Sentence examples for mutations are enough from inspiring English sources

In this regard, it has been reported that only two mutations are enough to introduce the adenylate kinase activity into guanylate kinase [ 38], suggesting a masking of guanylate kinase assignment by adenylate kinase.

This enzyme shares ∼50% sequence identity with CGTases, but does not form CDs, although, a few mutations are enough to change it into a CD forming enzyme (Beier et al. 2000).

It is plausible to think that the evolutionary pressure should also favor mutations that cause high initiation rate and more effectively affect the initiation rate of the same set of high expression genes, because small numbers of mutations are enough to change the initiation rate rather than changing the codon bias of entire coding region.

The daf-16 mutation was enough to rescue the daf-2 defect and the double mutants showed a wild-type phenotype for the roaming/dwelling behavior (Fig. 4).

This positively charged pocket on the surface of PolDom stabilizes the enzyme-DNA binary complex, and a single point mutation is enough to abolish this interaction (Brissett et al., 2007).

Since one frame-shifting mutation is enough to transform a copy of gene i into a pseudogene, we can approximate its time to inactivation, T ko, by (3) T ko ≈ 1/(l i * μ bp * f ko ) where f ko is the factor that specifies the frequency of frame-shift or other knock-out mutations relative to μ bp, the synonymous point mutation rate/basepair/generation, and l i is the total length of gene i.

Missense mutations in SMN2 are enough to abrogate splicing factor arginine/serine-rich 1 (SFRS1/SF2/ASF) binding and promote exon skipping of exon 7 [72] in cases of SMA.

The periodic selection model assumes that beneficial mutations are rare enough that they will not occur simultaneously in multiple individuals within a population, which may not be correct.

Generally, databases of kinetic measurements [ 168, 169] are growing and if functional effects of mutations are large enough, they can be measured in experiments or observed while evolving in vitro [ 170- 179].

If the underlying patterns are not caused by other processes and the selection coefficients of the corresponding mutations are large enough, then advantageous mutations can stop Muller's ratchet.

It means that the 20%% mutation factor and the 20 generations are enough to ensure the convergence of the genetic algorithm.