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In the two species, the mutations are different, and the molecular mechanism by which less melanin is produced is different, too.
Although the phenotypes arising from these mutations are different, suggesting different mechanisms of pathogenesis, we present evidence that apoptosis may be the final common pathway of the disease process linking genotype to phenotype.
And even in one embryo harboring mutations, the somatic mutations are different [ 5, 33].
Similar modification will be required for other populations where the frequencies of BRCA1 and BRCA2 mutations are different (e.g., the Icelandic).
It is important to note here, however, that these Dsk mutations are different from the oncogenic human GNAQ mutation at codon position 209 [ 33].
Molecular analysis would confirm hereditary hemochromatosis, but it has a variable diagnostic sensitivity because the mutations are different in different geographic areas.
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The mean number of mutations was different between African-Americans (151.31) and European-Americans (277.63).
The development of genotypic mutations was different in CSF and plasma, suggesting discordant viral evolution.
In the end, the doctor wouldn't see a remission of the patient's cancer if driver mutations were different across its metastases.
Yet even though the squamous cell cancers analyzed in the study often had mutations in genes for these enzymes, the genes and the mutations were different in different patients.
All mutations were different, indicating a lack of a founder effect in the form of jackpot mutations.
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