Sentence examples for mutations are deleterious from inspiring English sources

In the presence of regulators, most mutations are deleterious.

Nor, the geneticists complained, had there been enough time for natural selection to do its work, given what they had discovered about the rate at which mutations occur, and the fact that most mutations are deleterious.

In the absence of Mad2p-dependent spindle checkpoint, both mutations are deleterious.

A high mutation rate is usually associated with a fitness cost, because most mutations are deleterious.

Mutation and recombination probabilities are uniform across the genome, and all mutations are deleterious.

Ordinarily K a / K s values much less than one are observed, indicating that most amino acid mutations are deleterious.

Let all mutations be deleterious.

In SIFT (http://sift.bii.a-star.edu.sg/) the M158V mutation, as well as the known mutation R155H, was not tolerated (p = 0.00), meaning that the mutation is deleterious.

Purifying selection decreases the frequency of mutations that prove to be disadvantageous to carriers in a given environment, the magnitude of this decrease depending on the degree to which the mutation is deleterious.

The variation effect predicting algorithms were unable to determine whether these mutations were deleterious or not.

Depending on the nature of the mutations being deleterious or beneficial, the sign of epistasis can be positive or negative.