Sentence examples for mutations are closely from inspiring English sources

Here, TET2 mutations are closely associated with DNMT3A mutations [ 86] and, even more intriguing, do occur together with IDH2 mutations [ 89- 91].

In summary, we identified a new gene panD whose mutations are closely associated with PZA resistance in PZA-resistant mutants and clinical isolates without pncA or rpsA mutations.

This surprising finding suggests that panD mutations are closely associated with POA resistance and that the C-terminus of the PanD protein may be involved in POA binding.

In summary, we found that panD mutations are closely associated with POA resistance in POA-resistant mutants lacking pncA and rpsA mutations.

The finding that panD mutations are closely associated with PZA resistance may offer yet a third mechanism of PZA resistance besides pncA and rpsA mutations.

Increasing evidence suggests that potential biological markers, including EGFR gene mutation, amplification, or protein expression, are associated with EGFR-TKI drug efficacy [6]– [9], whereas K-Ras mutations are closely related with drug resistance [12], [13].

The alteration (increased G mutations) is closely associated with SHM and/or AID hotspots and causes a G over C strand bias.

EGFR protein expression, EGFR copy number and EGFR mutations were closely related to each other.

TP53 mutations were closely associated with older age, lower white blood cell (WBC) and platelet counts, FAB M6 subtype, unfavorable-risk cytogenetics and CK, but negatively associated with NPM1 mutation, FLT3/ITD and DNMT3A mutation.

The suaA mutations were closely linked to each other and were shown not to recombine in large numbers of progeny, making it likely that they were all mutations within the same gene (Sealy-Lewis 1987).

Studies across diverse taxa have shown that attenuation of IIS signaling by calorie restriction and IIS-related mutatisns is closely tied to slow aging and extended lifespan, and to improved old-age survival [ 54, 55].