Sentence examples for mutations and usage of from inspiring English sources

This removes hard to predict samples, as sometimes even relatively minor changes in the protein sequence (e.g. point mutations and usage of C- and N-terminus tag to ease purification) may change the final outcome of the crystallization.

One reason could be due to well-known and very important factors such as familial history, genetic mutations, menstrual cycles, and usage of oral contraceptives [ 139, 140].

The compelling history and usage of "mansplain".

The present results strongly indicate that the tendencies of nucleotide mutations and codon usage are characteristic of a genetic system specific to each species and oranelle, but the amino acid dependences of selective constraints are more specifc to each type of amino acid than each species, organelle, and protein family.

Interestingly, these exon-skipping mutations allowed usage of cryptic splice acceptor sites within intron four.

These point mutations promote usage of an alternate splice donor site located within exon 11 (11 3).

Because recombination has been implicated in immune evasion, the acquisition of drug-resistance mutations, and alterations of viral co-receptor usage, any attempt towards the successful eradication of HIV-1 requires therapeutic approaches targeting tissue macrophages.

However, signatures of selection on both nonsynonymous mutations and on codon usage persist in all heterochromatic regions.

Importantly, others show that cancer cells with IDH mutations become insensitive to treatment with mutant IDH inhibitors in vivo, owing to the metabolic rewiring and enhanced usage of the TCA cycle (Grassian et al., 2014; Tateishi et al., 2015).

Notably, there was a direct correlation between the higher frequencies of drug-resistance mutations and cross-resistance with previous usage of antiretroviral (ARV) therapy in both groups.

This mutation leads to the usage of the more proximal PAS and to the expression of a transcript with a shortened 3′UTR and a potentially higher stability.