Sentence examples for mutations and test from inspiring English sources

We suggest that it might protect from mutations, and test this hypothesis.

We then examine chromosomal resistance mutations and test whether the molecular mechanism or the biochemical basis effect the cost of resistance.

This abundance of information places new requirements on traditional disease models, which have the potential to be used to confirm newly identified pathogenic mutations and test the efficacy of emerging therapies.

The primary aims of this study were to examine the phenotypes associated with sarcomere protein (SP) gene mutations and test the hypothesis that variation in non-sarcomere genes modifies the phenotype.

It would then require additional work to identify and confirm all the gene mutations in a given mouse, as well as additional breeding to segregate mutations and test mutant mice with only one gene mutation, all of which increases breeding times and cage costs.

These include phenotypic culture based methods, tests for gene mutations and tests based on bacteriophage replication.

Here, we present a novel approach to analyzing correlated mutations and testing their validity.

Full details of the BRCA1 and BRCA2 mutation testing have been reported elsewhere and included: sequencing, protein truncation testing, two-dimensional gel electrophoresis, screening for large genomic alterations, testing for Ashkenazi founder mutations and testing for duplication of exon 13 of BRCA1 [ 3, 12].

Annotation of the likely functions of the gene products affected by these mutations and tests of the likelihood of functional disruption by each mutation can narrow the list of candidate polymorphisms.

In the course of this analysis we have re-examined the effects of dCTCF null mutations, and tested whether dCTCF proteins lacking the CP190 interaction domain or the dCTCF dimerization/multimerization domain can rescue the null mutation.

In a recent study Tate and co-workers [ 42 ] improved the stability of the β1-adrenergic receptor by making point mutations and testing the resulting mutants for activity as a function of temperature.