Sentence examples for mutations and shift from inspiring English sources

However, a high genetic diversity of BTV exists that is a consequence of both drift (i.e., point mutations) and shift (i.e., reassortment of individual BTV gene segments) so pathogenicity even within a serotype may be highly variable (5 ).

Internally, mutations and shifting genetic backgrounds change the genetic context in which genes are expressed.

Likewise, the identified modes of negative regulation give expected results, with non-sense mutations and frame shift deletions consistently negatively associated with TSG mRNA expression.

In this study we have focused on the role of nonsense mutations and frame shift indels that cause premature termination codons (PTCs) in chimpanzee protein coding genes.

Thus, deletion mutations and registry shifts can enhance proteins through structural rearrangements not possible by substitution mutations alone.

The probability of a protein having amino acid mutations and frame-shifts in cancer, events which are independent, was defined as the product of the respective p-values.

Although the majority of predicted L1 elements contain both ORF1 and ORF2, all but one of them carry mutations and frame-shift interruptions or in-frame stop codons.

Five substitution mutations and one frame shift mutation have been identified in human RRS (Table  4 and Figure  5B) [ 55].

Although a recent study has identified a small minority of head and neck squamous carcinoma patients with point mutations and one frame shift mutation [31], there is currently no reported evidence indicating such point mutations affect LIMD1 function.

Conventional approved antiviral drugs such as amantadine and oseltamivir [ 1] which are helpful to control the spread of influenza disease from the host cell [ 2] may not be suggested any longer due to various genetic drift and shift mutations which cause alterations in the antibody-targeted surface glycoproteins [ 3] and negative side effects and rapid emergence of resistant variants [ 4, 5].

Among 26 melanoma resection specimens, we here describe three silent point mutations and two frame shifts of the PTEN/MMAC1 cDNA sequence.