Sentence examples for mutations and several from inspiring English sources

Therefore, with continuous occurrence of mutations and several cascades of evolution, a substantially transformed cell will emerge and expand as a subpopulation.

Many new mutations and several important signaling pathways have been identified.

Within the 77 primary gastric carcinomas we found two EGFR somatic mutations and several EGFR polymorphisms in exon 20.

Resistance to raltegravir arises due to a combination of few primary mutations and several additional secondary mutations.

Previous studies have suggested a relation between EGFR mutations and several clinicopathological factors, but whether EGFR status differs according to age group remains unclear.

To our knowledge, PDGFRB mutations have never been described in MPNST, although some somatic PDGFRA mutations and several polymorphisms have been reported [ 19].

We investigate the dynamics of cancer initiation in a mathematical model with one driver mutation and several passenger mutations.

Compared with them, paralogs of Group I are less degenerated, having only one reading frame shift mutation and several stop codons.

The D-loop of mtDNA appears particularly to be susceptible to mutation, and several insertions, deletions, and point mutations have been identified in this region in breast cancer tissues (Lee et al, 2010).

However, it is likely that tumors with other less common BRAF mutation such as c.1798_1799GT > AA (V600K) mutation, c.1798_1799GT > AG (V600R) mutation, c.1799_1800TG > AA (V600E rare variant) mutation, and several other codon 600 mutations could also respond to treatment with BRAF inhibitors.

His nadir CD4 count was 70 cells/mm and his last genotypic resistance test prior to starting TDF/FTC/ATV/r contained multiple thymidine analog resistance mutations, M184V, and several NNRTI-resistance mutations.