Sentence examples for mutations and reduced from inspiring English sources

Finally, we found that the fitness cost of resistance also contributed significantly to the observed variation in CS and CR, despite some collinearity between efflux-related mutations and reduced fitness.

Now many of techniques are used in diagnosing the biological and clinical differences of leukemic cells, including the acquisition of new chromosomal abnormalities, gene mutations, and reduced responsiveness to chemotherapeutic agents [10] [13].

In this study, we observed an overall association between BRCA1/2 mutations and reduced life expectancy after excluding deaths following diagnosis of the cancers that have been shown to be related to these mutations.

Consequent selection of cells with mutations and reduced radiosensitivity can lead to disease progression and treatment-resistance.

We asked whether an older arrangement accumulates more LD due to new mutations and reduced genetic exchange.

The interaction of Kapβ2 with RAM was inhibited by the PY1AA or PY1/2AA mutations and reduced by the PY2AA mutation.

The nature of multiple plastomes allows for highly efficient gene conversion in asexual genetic systems, correcting mutations and reducing the mutational load of plastomes (Khakhlova and Bock 2006).

Our results provide a rationale for testing a hypothesis that early therapeutic vaccination (e.g., within two months p/s) may prevent reverse mutations and reduce viral set point.

Mitochondria accumulate DNA mutations and reduce ATP production necessary for cellular metabolism.

The BoxG1 mutation and reduced expression of glmUS may thus confer an advantage by reducing excess synthesis of these components.

In a related report, Cbl mutation and reduced EGFR ubiquitination inhibited early endosome fusion and EGFR degradation in HEK 293 cells [ 20].