Sentence examples for mutations and perhaps from inspiring English sources

More divisions means more mutations and perhaps more cancers.Organs renew themselves from special cells called stem cells that, when they divide, produce one daughter cell which is another stem cell, and a second which goes on to generate descendants that are cells needed by the tissue in question.

In contrast, p53 staining was not predictive of survival of patients with type II endometrial carcinomas (Fig 6F), likely because the vast majority of these tumours contain TP53 mutations and perhaps because some of the non-p53 staining tumours may have lost p53 function by gene deletion or truncating mutation, which cannot be detected in our assay.

The formation of DPCs may be one of the mechanisms that induces mutation and perhaps cancers in arsenicosis patients.

We have realized that CNVs are as important as SNPs to human mutation and perhaps even more important with regard to human sporadic traits [ 87, 127].

Tumors with MET and NRAS mutations also have an unexpectedly high frequency of co-occurring mutations, which suggests that they occur as a second mutation and perhaps later in the etiology of the tumor.

If there is a very low replication rate, then the race between repair and replication will be in favor of repair, thereby reducing the probability for producing a mutation and perhaps creating a practical threshold.

Our analysis of independent samples from four case-control studies provided some support of the observation by Tavtigian et al. [ 31, 32] that this mutation (and perhaps other similar missense mutations with dominant-negative activity) confers a higher risk of breast cancer than do protein-truncating mutations.

A study of fruit flies, reported in tomorrow's Nature, suggests that these silenced mutations--and perhaps helpful ones, too--may surface when one particular heat shock protein is itself mutated or must cope with potentially damaging heat or cold.

It appears to be generally nongenotoxic, but all asbestos fiber types can induce chromosomal mutations and aneuploidy, perhaps through their ability to disrupt normal chromosome segregation.

Based on these results (Fig. 11) and the fact that the parents of this patient have approximately two-times less ACE compared to the population norm (Fig. 1), such an approach might work for patients with this mutation (Q1069R) and perhaps others, such as the patient in Japan with the Δ1141 1152 ACE deletion in the C-domain [45].

Indeed, it has been shown that p53 mutation precedes (and perhaps leads to) aneuploidy in Barrett's tissues (Neshat et al, 1994; Prevo et al, 1999).