Sentence examples for mutations and multiple from inspiring English sources

In particular, this new technology could allow therapeutic solution for genes as complex as the dystrophin gene with a variety of mutations and multiple isoforms.

To our knowledge, our present study is, to date, the largest single study of an aromatase inhibitor given in the neoadjuvant setting in which the relationship between response to treatment, PIK3CA mutations and multiple GSs of PI3K has been examined.

Models of adaptation that include concurrent mutations and multiple concurrent mutations on individual genotypes [ 3, 9] may provide more realistic frameworks for investigating the properties of adaptation in large microbial populations.

The close associations between single gene mutations and multiple organ defects (e.g. Smith-Lemli-Opitz syndrome[ 30]) further questions the prospective utility of classifying the resulting syndromes rather than causes of inductive or disruptive effects.

To explore the search space efficiently, polynomial mutation and multiple molecule collision operators are introduced in the inter-molecular collision and synthesis operator.

We observed intratumor genetic branching patterns of multiple complexities, ranging from a single shared mutation to a shared mutation and multiple nonshared mutations within a tumor.

Alternatively, the strong connection between the mutation and multiple copies in E. necator could also be a result of a fitness cost due to the Y136F mutation.

Additionally, differential expression signatures associated with lowfat diet treatments were significantly similar to those of dwarf mutations (especially the Ghrhr lit / lit mutation) and multiple CR treatments (see Fig. 5).

Women with a BRCA1 mutation and multiple cases of BRCA1 mutations in their families can have a lifetime risk in excess of 80% of developing breast cancer, a 40 – 60% chance of developing ovarian cancer and possibly an increased risk of developing colorectal cancer (Ford et al, 1994).

The CLC Probabilistic Variant Detection algorithm was used to determine small mutations (single and multiple nucleotide polymorphisms, short insertions and short deletions).

Alternatively to multiple independent origins one might theoretically invoke ancestral presence of the mutations and then multiple independent reversions to the normal allele.