Sentence examples for mutations and many from inspiring English sources

For example, the deep mutational scanning finds that there is strong purifying selection against stop-codon mutations and many nonsynonymous mutations, but that there is only weak selection against synonymous mutations.

That is, there are likely only several relevant driver mutations and many additional passenger mutations.

The cleavage of a range of proteins is affected by presenilin mutations and many would affect the synapse.

All patients described to date carry compound heterozygous GLE1 mutations, and many have one copy of the FinMajor allele (Nousiainen et al., 2008).

Several biological processes could individually or in combination solve this genomic decay paradox, including paternal leakage of undamaged DNA from sexual sister species, compensatory mutations and many others.

Importantly, Y181C forms the foundation for high-level ETR and RPV resistance as an addition of some single mutations and many double mutations causes high-level resistance to these drugs.

There are now more than 2,600 genetic diseases on record, any one of which may be caused by a radiation-induced mutation, and many of which we're bound to see more of, because we are artificially increasing background levels of radiation.

RNA viruses exhibit extremely high mutation rates and given the large population sizes observed in both experimental and natural infections with these viruses, every possible point mutation and many double-mutation combinations could theoretically be generated during each replication cycle within a population.

The presented search engine, http://www.integromedb.org, has been designed for browsing available data on gene regulation, gene expression, protein-protein interactions, pathways, metagenomics, mutations, diseases, and many other gene- and protein-related data.

TP53 is mutated at the end of the mutation pathway, and many cancer cells without a mutation in this gene can be observed within the specimen [ 22- 25].

While this may simply point to underlying genomic instability of myeloid neoplasms, studies in acute myeloid leukemia have not generally found increased absolute numbers of mutations [ 74], and many mutations are found as a result of aging alone in individuals without any significant hematolymphoid malignancy [ 75– 75].