Sentence examples for mutations and indicate from inspiring English sources

Our observations, therefore, provide a minimum figure for the prevalence of ten pathogenic mutations and indicate that mtDNA mutations are amongs the most common pathogenic alleles in the general population.

A significant ratio of fixed replacement to fixed synonymous mutations leads to rejecting the neutral mutation hypothesis and indicates adaptive fixation of selectively advantageous mutations.

Other studies detect at least several possible V3 loop mutation pathways [19] and indicate the twofold larger heterogeneity of the X4-tropic viruses over the R5-tropic.

On the contrary, Vogler et al. [ 20] did not observe a pure "strain" effect on mutation rate and indicated that instead allele size at individual loci did affect the mutation rate.

In fact, the variation in sequence (including silent mutations) and phenotype indicated that all sequenced isolates were from different clones.

This showed that appropriate mutations prevent processing and indicated an absence of alternative sites at the 83/30 and 30/38 positions in MSP1-F.

Among birds they have documented reduced longevity and male fertility, smaller brains, and mutations that indicate significant genetic damage compared with the same species in areas of low radiation.

Mutations in the TP53 gene are the most frequent genetic changes in human cancers, and the spectrum of mutations can indicate tumour aetiology and molecular pathogenesis (Levine et al, 1991; Greenblatt et al, 1994).

Overexpression of β-catenin and KRAS mutations may indicate that ACF constitute a premalignant stage [ 16].

Sure Genomics says initial reports will be made available with physician oversight, including the BRCA1 and BRCA2 gene mutations, which indicate an increased risk of female breast and ovarian cancers.

Together with the immunohistochemical analysis, the patterns of shared and private mutations indicate early divergence of low- and high-grade foci.