Sentence examples for mutations and increases from inspiring English sources
While we observed EGFR DNA sequence mutations and increases in EGFR and HER2 gene copy number in several of our specimens, we were unable to statistically correlate the presence of any of these molecular features with response.
However, we recognize that our summary may not contain all Nav channel disease-related mutations owing to abundant literatures reporting Nav channel disease-related mutations and increasing volume of work describing new findings.
An overall test of association for men and women together showed a statistically significant association between BRCA1/2 mutations and increased non-cancer mortality (p = 0.024).
Positive selection acts towards introducing nonsynonymous mutations and increasing the diversity of the population.
A correlation between mtDNA mutations and increased ROS contents in primary leukemia cells isolated from patients has been shown [ 40].
The mutations and increasing virulence of MDV are thought to be responsible for the occurrence of MD on vaccinated farms.
Furthermore, a relationship between progressive increases in mutations and increasing histologic aggressiveness has not been identified for other common cancers such as breast, lung, or prostate.
High PKB activity in pancreatic cancer tumors is associated with resistance to apoptosis, higher rates of metastasis and mutations, and increased proliferation and uninhibited growth.
Cancer is commonly thought as the result of progressive accumulation of random mutations and increased deregulation of key molecular pathways (somatic mutation theory of carcinogenesis, SMT) [ 1].
In addition, a study of 833 patients with primary breast carcinoma revealed a strong association between p53 mutations and increased vascular endothelial growth factor (VEGF) expression.
Interestingly, reciprocal associations between hypolipobetaproteinemia, a condition caused by APOB mutations, and increased longevity have been described (Glueck et al., 1976; Arai et al., 1997).
