Sentence examples for mutations and includes from inspiring English sources

The ATP binding site of kinases has proven to be a "hot spot" for kinase mutations and includes a "gatekeeper" region shown to be difficult to block with inhibitors and their new more potent derivatives.

Seventeen of these were novel mutations and included missense, nonsense and splice site mutations as well as deletions and a single-base insertion.

We discuss deviations for large mutation rates and including back mutations.

Factors that influence its processing via CMA including various α-synuclein mutations and modifications including oxidative damage and S129 phosphorylation can lead to α-synuclein accumulation.

Large-scale DNA sequencing has revealed a complex pattern of lesions and mutations that includes mutational hotspots and mutations that are linked to specific sequences of bases.

In all, 617 samples were tested for BRCA1 and BRCA2 mutations and were included in our analysis.

Smaller mutations are more common and include point mutations, in which substitution of a single nucleotide base occurs, and deletion or insertion mutations, which involve several bases.

Affected genomic regions were highly heterogeneous and included mutations of single genes.

On the contrary, association mapping could exploit all recombination events and mutations including historical and evolutionary recombination in natural populations with unobserved ancestry [ 10].

We detected 19 mutations in PR8 and 29 mutations (including the two tracer mutations) in PR8mut with a frequency of 0.5% or higher.

However, expressed transcripts from the tammar wallaby show no evidence of this mutation and also include the leader peptide.