Sentence examples for mutations and how from inspiring English sources
By contrast, we know less about the mutational factors that influence the evolutionary potential of a population and species, such as the rate at which mutations arise, the relative frequencies of different types of mutations, and how variable the mutational process is across the genome [ 3– 5].
That is the group of nongovernmental experts that originally voted 22 to 0 to recommend that the paper be published only after details on specific mutations and how they were made were redacted.
Still, even if the numbers aren't definitive, the study is "important" because it "establishes a framework for thinking about loss-of-function mutations and how to prioritize them," she says.
Little is known about the early hierarchy in targeting CTL epitopes and relative immunodominance, the timing of escape mutations, and how efficient novel CTL responses can be generated towards epitope variants in acutely infected humans.
The exact location of these disease causing mutations and how their position relates to the JH1 domain are not known.
We asked whether or not TEDG framework can reconstruct the order of mutations and how many patients are required.
Geneticists are less familiar with his contributions to mutation and how he related the process of mutagenesis to the gene and distinguished gene mutations from other genetic and epigenetic events such as polyploidy, chromosome rearrangements, and position effects.
By use of NetEffects, we were able to suggest possible paths affecting FOXO-mediated lifespan given a single mutation and how these differ across species, thus generating hypotheses for further investigation.
Our study illustrates caveats in the interpretation of rare variants identified by current strategies for whole-genome sequencing and how rare variants can be useful in tagging a nearby non-coding true disease-causing mutation and how changes in coverage depth can reveal repeat expansions.
Further studies are required to determine which gene or genes are mutated and how the mutations that led to their inactivation were selected for in the first place.
Understanding how these proteins are mutated and how these mutations affect their regulation will be crucial for identifying new therapies and treatments for breast cancer.
