Sentence examples for mutations and have from inspiring English sources

Structural modeling and energetic analysis of the mutational hotspots have suggested a common molecular mechanism of kinase activation by cancer mutations, and have allowed to reconcile the experimental data.

If that sounds potentially dangerous, it is: Such genes are often the culprits behind tumor-causing mutations and have been implicated in several neurological diseases.

It is assumed that direct DNA-reactive carcinogens initiate carcinogenesis by inducing mutations and have low-dose linear dose response curves, whereas carcinogens that operate through a nonmutagenic MOA may have nonlinear dose responses.

Mutations that block the synthesis or accumulation of PA during seed development are called lpa mutations and have been isolated from some important crops, including maize (Raboy et al. 2000; Pilu et al. 2003), barley (Dorsch et al. 2003), rice (Liu et al. 2007), soybean (Hitz et al. 2002), and wheat (Guttieri et al. 2004).

We have adapted the use of mRNA as the basis for testing for JAK2 mutations and have shown that RNA allows more sensitive detection of mutations than does DNA at early stages of disease [7] [9].

Visual inspection of the most recent recombination events occurred in this region shows that while the sequence of the rrgA, srtB and srtC genes contain evidence of recent crossover events, the rrgB, rrgC and srtD genes have evolved mainly through the accumulation of mutations, and have been exchanged amongst the different strains only as discrete units.

It is caused by sarcomeric gene mutations and has variable phenotypic expression.

Beerenwinkel's model considered only advantageous mutations and had a fixed mutation rate.

Chronic inflammation generates a stromal environment susceptible to mutations and has been linked to tumor initiation and growth.

Young upstarts Municipal Waste recently released an instant crossover thrash classic called Hazardous Mutation and have managed to perfectly capture the spirit of that age without having actually been there.

These data appear consistent with (iv) above, rapid mutation, and have now been included.