Sentence examples for mutations and haplotypes from inspiring English sources

A number of embryonic lethal mutations and haplotypes have been identified using novel approaches.

Several of the studies applied to mtDNA genes have yielded negative results, even though in some families migraine was reported to segregate with the Leber mtDNA 14484 mutation [79], and mtDNA mutations and haplotypes (haplotype U) have been associated with juvenile migraine stroke [80, 81] and with cyclic vomiting, considered a migraine equivalent in the pediatric population [82 84].

In this study, we screened pregnant women with APCR for known mutations and haplotypes in the factor V gene.

Use of such databases in combination with methods to phase de novo mutations and haplotypes resulting from recent recombinations could both permit increased haplotype quality and reduce the need for genetic and molecular haplotyping in patients from these populations.

Incidentally, human genetic variation studies based on autosomal, Y-chromosomal and mt-DNA markers have suggested that north Indians carry high frequency of Caucasian specific mutations and haplotypes [ 37, 38].

To look for resistance-associated point mutations and haplotypes, the complete coding region of Pfdhfr (dihydrofolate reductase) and Pfdhps (dihydropteroate synthase) was amplified and sequenced (ABI 3100 Genetic Analyser, Applied Biosystems, Courtaboeuf, France) as described (9 ).

PCR-Restriction enzyme analysis (PCR-REA) was applied to identify: FVL, FV Cambridge, FV Hong Kong mutations and Haplotype (H) R2, R3 alleles in the factor V gene.

C. gloeosporioides sensu lato isolates from Trinidad had more segregating sites (S) in the ACT and ITS sequences than those from Mexico as well as a greater number of mutations (Eta) and haplotypes (h) than Mexico.

Ancient haplotypes are named according to the letter of their haplogroup supplemented by a number or a number and a letter depending on how far they are from the basal node (for example: haplotype D3 is separated from D by 1 mutation, and haplotype D3a by 2 mutations).

As is well recognized, both the spectrum of allele frequencies for "causal" mutations and proxy haplotypes can vary widely across population groups [15].

The relationship between causal mutations and the haplotypes have been regarded as a tool for genetic researches----first finding association to a haplotype, and then subsequently identifying the causal mutations that it carries [ 49].