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No relationship was found between PIK3CA mutations and clinicopathological characteristics and clinical outcome in gastric cancer.
The relationship between TP53 mutations and clinicopathological parameters is shown in Table 1.
The relationship between LKB1 mutations and clinicopathological characteristics and other common oncogene mutations in NSCLC is inadequately described.
The relationships between KRAS/BRAF mutations and clinicopathological factors, including p-ERK1/2 expression are shown in Table 2.
The present study assessed the status of EGFR mutations in elderly patients with NSCLC and examined the relations of EGFR mutations and clinicopathological factors to outcomes.
The statistical analysis revealed no significant correlation between p53 mutations and clinicopathological data, although mutations appear to occur more frequently in squamous cell carcinomas (7 of 18) than in adenocarcinomas (2 of 15).
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We assessed the relationship between PIK3CA mutation and clinicopathological and molecular features in each cohort according to MSI status (Table 4).
Possible associations between KRAS mutation and clinicopathological parameters of CRCs were investigated using the χ-test or Fisher's exact test (when appropriate) for categorical variables and using Student t-test or Mann–Whitney U-test (when appropriate) for continuous variables.
There was no relationship between the type of mutations and any clinicopathological parameter.
No significant associations were found between PIK3CA mutations and classical clinicopathological characteristics (Supplementary Table S1).
Previous studies have suggested a relation between EGFR mutations and several clinicopathological factors, but whether EGFR status differs according to age group remains unclear.
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