Sentence examples for mutations and appear from inspiring English sources

Tetraodon contains five tandem-arrayed Ugt5b genes two of which have frame-shift mutations and appear to be pseudogenes.

Both plants and animals need to avoid the inheritance of accumulated mitochondrial mutations and appear to use different mechanisms to accomplish that.

Most of the mutations described for developmental anomalies are missense mutations and appear mainly on the phosphatase and C2 domains, e.g. (30, 32, 38, 39).

Clusters with the largest number of maternal transcripts also display an over-representation of known lethal mutations and appear to evolve at normal or even reduced rates compared with estimates for the whole genome.

WNT subgroup tumours (~15% of total) are characterised by activation of the wnt/wingless pathway through CTNNB1 mutations, and appear to originate from progenitor cells derived from the dorsal brain stem [ 4].

Gly48Ala/Ser/Thr/Gln/Leu are extremely rare PR mutations that occur primarily in viruses containing multiple PI-resistance mutations and appear to have similar but weaker effects on PI susceptibility than do Gly48Val and Gly48Met.

These variants represented silent mutations and appeared to be random mutational events, possibly resulting from the accelerated division rate of the transformed cells.

The third process, which we termed KC for "kinetically complex", since we could not determine the "hit number" accurately because of the short range of doses over which it was expressed, is also associated with suppressor mutations, and appears to be an inducible process (A96).

For instance, mutation m.3635G>A was reported in several LHON families without the three primary mutations and appeared to be one of LHON primary mutations in Chinese families [11] [13].

Similarly, the five Ugt5b (5b1 to 5b5) genes are clustered on the chromosome 1; however, the Ugt5b5 gene has four nonsense mutations and two frameshift mutations and appears to be a pseudogene.

Differentiated thyroid carcinomas (in contrast to the rarer anaplastic form) are unusual among human cancers in displaying a remarkably low frequency of p53 mutation and appear to retain wild-type (wt) p53 function as assessed by the response of derived cell lines to DNA damage.