Sentence examples for mutations alter an from inspiring English sources

Mutations alter an organism's genotype and occasionally this causes different phenotypes to appear.

Here, Bloomfield et al. used genome sequencing to reveal that these mutations alter a gene that encodes a protein called Neurofibromin.

These mutations alter a single DNA nucleotide, which subsequently changes the identity of an amino acid in one of the proteins produced by the cell.

Many of these mutations alter a section of the protein called the homeodomain, and therefore interfere with the ability of NKX2-5 to bind to DNA or associate with other important cardiac proteins called cofactors.

For instance, mutations altering a particular residue of MreB confer a range of different cell widths in E. coli (our unpublished observations).

The missense mutation altered an amino acid residue that is uniformly conserved from Escherichia coli to Homo sapiens (humans).

23 We found that the m.14439G>A mutation altered an evolutionarily conserved proline to a serine in the hydrophilic inner membrane space of the ND6 protein 22 (Fig. 3C).

max-2 (cy2 ) is a point mutation altering a conserved residue in the kinase domain, suggesting that it causes strong kinase loss of function (Lucanic et al. 2006).

Large deviations from our linear model of expression divergence would be possible if a single mutation altered a gene's expression dramatically, and this event had a cascading effect on the expression of other genes.

The importance of the MAM domain is nevertheless emphasized in studies from Drosophila in which a point mutation altering a highly conserved aspartic acid residue in the MAM domain to arginine renders dALK (Drosophila ALK) inactive [ 10].

A mutagenesis approach to finding modulators of protein aggregation, which also used C. elegans strain AM141, reported just one locus at which mutations alter aggregation: an uncharacterized gene termed moag-4 (van Ham et al., 2010).